3u2q
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u2q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u2q RCSB], [http://www.ebi.ac.uk/pdbsum/3u2q PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u2q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u2q RCSB], [http://www.ebi.ac.uk/pdbsum/3u2q PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/EFTU1_ECOLI EFTU1_ECOLI]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118] May play an important regulatory role in cell growth and in the bacterial response to nutrient deprivation.[HAMAP-Rule:MF_00118] [[http://www.uniprot.org/uniprot/THCL_PLARO THCL_PLARO]] Has bacteriocidal activity against Gram-positive bacteria and a few Gram-negative bacteria. It is particularly active against anaerobes. Inhibits bacterial protein biosynthesis by preventing the formation of a stable complex between the elongation factor Tu (EF-Tu), GTP and tRNA, hindering the activation of EF-Tu. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 10:39, 25 December 2014
EF-Tu (Escherichia coli) in complex with NVP-LFF571
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