2px7

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PX7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PX7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, TTHA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 Thermus thermophilus HB8])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, TTHA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 Thermus thermophilus HB8])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [http://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [http://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [http://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [http://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ISPD_THET8 ISPD_THET8]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
[[Category: Thermus thermophilus hb8]]
[[Category: Thermus thermophilus hb8]]
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[[Category: Chang, S-H.]]
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[[Category: Chang, S-H]]
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[[Category: Chen, L-Q.]]
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[[Category: Chen, L-Q]]
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[[Category: Chen, L.]]
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[[Category: Chen, L]]
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[[Category: Ebihara, A.]]
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[[Category: Ebihara, A]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu, S]]
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[[Category: Lee, D.]]
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[[Category: Lee, D]]
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[[Category: Liu, Z-J.]]
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[[Category: Liu, Z-J]]
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[[Category: Nguyen, D.]]
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[[Category: Nguyen, D]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Rose, J P.]]
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[[Category: Rose, J P]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Shinkai, A]]
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[[Category: Shinkai, A.]]
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[[Category: Tsukuda, M]]
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[[Category: Tsukuda, M.]]
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[[Category: Wang, B-C]]
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[[Category: Wang, B-C.]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama, S.]]
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[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
[[Category: Ispd]]
[[Category: Ispd]]
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[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Secsg]]
[[Category: Secsg]]
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[[Category: Southeast collaboratory for structural genomic]]
 
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Ttha0171]]
[[Category: Ttha0171]]

Revision as of 10:42, 25 December 2014

Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8

2px7, resolution 2.20Å

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