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2cz1
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2cz1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CZ1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2cz1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CZ1 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cyz|2cyz]], [[2cz0|2cz0]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cyz|2cyz]], [[2cz0|2cz0]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2cz1 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cz1 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2cz1 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cz1 TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. [[http://www.uniprot.org/uniprot/NHAB_RHOER NHAB_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Nitrile hydratase]] | [[Category: Nitrile hydratase]] | ||
[[Category: Rhodococcus erythropolis]] | [[Category: Rhodococcus erythropolis]] | ||
| - | [[Category: Endo, I | + | [[Category: Endo, I]] |
| - | [[Category: Hashimoto, K | + | [[Category: Hashimoto, K]] |
| - | [[Category: Kamiya, N | + | [[Category: Kamiya, N]] |
| - | [[Category: Kawano, Y | + | [[Category: Kawano, Y]] |
| - | [[Category: Nakayama, H | + | [[Category: Nakayama, H]] |
| - | [[Category: Odaka, M | + | [[Category: Odaka, M]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Takio, K | + | [[Category: Takio, K]] |
[[Category: Cysteine-sulfenic acid]] | [[Category: Cysteine-sulfenic acid]] | ||
[[Category: Cysteine-sulfinic acid]] | [[Category: Cysteine-sulfinic acid]] | ||
| Line 44: | Line 46: | ||
[[Category: Photo-reactive]] | [[Category: Photo-reactive]] | ||
[[Category: Post-translational modification]] | [[Category: Post-translational modification]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 10:44, 25 December 2014
photo-activation state of Fe-type NHase with n-BA in anaerobic condition
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Categories: Nitrile hydratase | Rhodococcus erythropolis | Endo, I | Hashimoto, K | Kamiya, N | Kawano, Y | Nakayama, H | Odaka, M | Structural genomic | Takio, K | Cysteine-sulfenic acid | Cysteine-sulfinic acid | Hydration | Lyase | National project on protein structural and functional analyse | Nitrile | Non-hem iron | Nppsfa | Photo-reactive | Post-translational modification | Rsgi
