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3a98
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a98 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a98 RCSB], [http://www.ebi.ac.uk/pdbsum/3a98 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a98 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a98 RCSB], [http://www.ebi.ac.uk/pdbsum/3a98 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ELMO1_HUMAN ELMO1_HUMAN]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.<ref>PMID:11595183</ref> <ref>PMID:12134158</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Fukui, Y | + | [[Category: Fukui, Y]] |
| - | [[Category: Hanawa-Suetsugu, K | + | [[Category: Hanawa-Suetsugu, K]] |
| - | [[Category: Ito, T | + | [[Category: Ito, T]] |
| - | [[Category: Kukimoto-Niino, M | + | [[Category: Kukimoto-Niino, M]] |
| - | [[Category: Mishima-Tsumagari, C | + | [[Category: Mishima-Tsumagari, C]] |
| - | [[Category: Sekine, S | + | [[Category: Sekine, S]] |
| - | [[Category: Shirouzu, M | + | [[Category: Shirouzu, M]] |
| - | [[Category: Terada, T | + | [[Category: Terada, T]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
Revision as of 10:44, 25 December 2014
Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1
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Categories: Homo sapiens | Fukui, Y | Hanawa-Suetsugu, K | Ito, T | Kukimoto-Niino, M | Mishima-Tsumagari, C | Sekine, S | Shirouzu, M | Terada, T | Yokoyama, S | Apoptosis | Cell membrane | Cytoskeleton | Dock2 | Elmo1 | Guanine-nucleotide releasing factor | Helix bundle | Membrane | Ph domain | Phagocytosis | Phosphoprotein | Proline-rich sequence | Protein-protein complex | Sh3 domain | Sh3-binding | Signaling protein
