4ggb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ggb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GGB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GGB FirstGlance]. <br> | <table><tr><td colspan='2'>[[4ggb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GGB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GGB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Atu3139 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=358 Agrobacterium tumefaciens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Atu3139 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=358 Agrobacterium tumefaciens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ggb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ggb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ggb RCSB], [http://www.ebi.ac.uk/pdbsum/4ggb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ggb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ggb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ggb RCSB], [http://www.ebi.ac.uk/pdbsum/4ggb PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A9CEQ8_AGRT5 A9CEQ8_AGRT5]] Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D-glucaro-6,3-lactone and linear D-glucarate.<ref>PMID:22493433</ref> <ref>PMID:24450804</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Agrobacterium tumefaciens]] | [[Category: Agrobacterium tumefaciens]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Bouvier, J T | + | [[Category: Bouvier, J T]] |
| - | [[Category: EFI, Enzyme Function Initiative | + | [[Category: EFI, Enzyme Function Initiative]] |
| - | [[Category: Gerlt, J A | + | [[Category: Gerlt, J A]] |
| - | [[Category: Imker, H J | + | [[Category: Imker, H J]] |
| - | [[Category: Morisco, L L | + | [[Category: Morisco, L L]] |
| - | [[Category: Sojitra, S | + | [[Category: Sojitra, S]] |
| - | [[Category: Vetting, M W | + | [[Category: Vetting, M W]] |
| - | [[Category: Wasserman, S R | + | [[Category: Wasserman, S R]] |
[[Category: Efi]] | [[Category: Efi]] | ||
[[Category: Enolase]] | [[Category: Enolase]] | ||
Revision as of 10:46, 25 December 2014
Crystal structure of a proposed galactarolactone cycloisomerase from agrobacterium tumefaciens, TARGET EFI-500704, WITH BOUND CA, DISORDERED LOOPS
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Categories: Agrobacterium tumefaciens | Almo, S C | Bouvier, J T | EFI, Enzyme Function Initiative | Gerlt, J A | Imker, H J | Morisco, L L | Sojitra, S | Vetting, M W | Wasserman, S R | Efi | Enolase | Enzyme function initiative | Isomerase | Proposed galactarolactone cycloisomerase | Structural genomic
