3lny

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lny OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lny RCSB], [http://www.ebi.ac.uk/pdbsum/3lny PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lny OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lny RCSB], [http://www.ebi.ac.uk/pdbsum/3lny PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PTN13_HUMAN PTN13_HUMAN]] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.<ref>PMID:15611135</ref> [[http://www.uniprot.org/uniprot/RPGF6_HUMAN RPGF6_HUMAN]] Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.<ref>PMID:12581858</ref> <ref>PMID:11524421</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 11:02, 25 December 2014

Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide

3lny, resolution 1.30Å

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