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1xpu
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xpu]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XPU FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xpu]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XPU FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=FPD:5A-(3-FORMYLPHENYLSULFANYL)-DIHYDROBICYCLOMYCIN'>FPD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=FPD:5A-(3-FORMYLPHENYLSULFANYL)-DIHYDROBICYCLOMYCIN'>FPD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xpo|1xpo]], [[1xpr|1xpr]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xpo|1xpo]], [[1xpr|1xpr]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xpu RCSB], [http://www.ebi.ac.uk/pdbsum/1xpu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xpu RCSB], [http://www.ebi.ac.uk/pdbsum/1xpu PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MEMA_METCA MEMA_METCA]] Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Berger, J M | + | [[Category: Berger, J M]] |
| - | [[Category: Brogan, A P | + | [[Category: Brogan, A P]] |
| - | [[Category: Kohn, H | + | [[Category: Kohn, H]] |
| - | [[Category: Park, B S | + | [[Category: Park, B S]] |
| - | [[Category: Skordalakes, E | + | [[Category: Skordalakes, E]] |
[[Category: Atpgamma]] | [[Category: Atpgamma]] | ||
[[Category: Rho transcription termination factor]] | [[Category: Rho transcription termination factor]] | ||
[[Category: Transcription-rna complex]] | [[Category: Transcription-rna complex]] | ||
Revision as of 11:13, 25 December 2014
Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB)
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