1ile
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ile]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ILE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ILE FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ile]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ILE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ILE FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ile FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ile OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ile RCSB], [http://www.ebi.ac.uk/pdbsum/1ile PDBsum], [http://www.topsan.org/Proteins/RSGI/1ile TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ile FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ile OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ile RCSB], [http://www.ebi.ac.uk/pdbsum/1ile PDBsum], [http://www.topsan.org/Proteins/RSGI/1ile TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SYI_THET8 SYI_THET8]] Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity).[HAMAP-Rule:MF_02003] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Fukai, S | + | [[Category: Fukai, S]] |
| - | [[Category: Konno, M | + | [[Category: Konno, M]] |
| - | [[Category: Nakama, T | + | [[Category: Nakama, T]] |
| - | [[Category: Nureki, O | + | [[Category: Nureki, O]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Schimmel, P | + | [[Category: Schimmel, P]] |
| - | [[Category: Shimada, A | + | [[Category: Shimada, A]] |
| - | [[Category: Tateno, M | + | [[Category: Tateno, M]] |
| - | [[Category: Vassylyev, D G | + | [[Category: Vassylyev, D G]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Aminoacyl-trna synthetase]] | [[Category: Aminoacyl-trna synthetase]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 11:16, 25 December 2014
ISOLEUCYL-TRNA SYNTHETASE
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