2fqw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fqw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQW FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fqw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOS:INOSINE'>NOS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOS:INOSINE'>NOS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fqx|2fqx]], [[2fqy|2fqy]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fqx|2fqx]], [[2fqy|2fqy]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmpC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160 Treponema pallidum])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmpC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160 Treponema pallidum])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fqw RCSB], [http://www.ebi.ac.uk/pdbsum/2fqw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fqw RCSB], [http://www.ebi.ac.uk/pdbsum/2fqw PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TMPC_TREPA TMPC_TREPA]] Binds purine nucleosides and may play a role in purine nucleoside uptake. May be part of an ABC-type nucleoside uptake system. Has highest affinity for guanosine, followed by inosine and adenosine. Has very low affinity for cytidine and does not bind thymidine.<ref>PMID:16418175</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Treponema pallidum]]
[[Category: Treponema pallidum]]
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[[Category: Brautigam, C A.]]
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[[Category: Brautigam, C A]]
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[[Category: Deka, R K.]]
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[[Category: Deka, R K]]
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[[Category: Machius, M.]]
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[[Category: Machius, M]]
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[[Category: Norgard, M V.]]
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[[Category: Norgard, M V]]
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[[Category: Tomchick, D R.]]
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[[Category: Tomchick, D R]]
[[Category: Abc transport system]]
[[Category: Abc transport system]]
[[Category: Inosine]]
[[Category: Inosine]]
[[Category: Ligand-binding protein]]
[[Category: Ligand-binding protein]]
[[Category: Transport protein]]
[[Category: Transport protein]]

Revision as of 11:17, 25 December 2014

PnrA from Treponema pallidum as purified from E. coli (bound to inosine)

2fqw, resolution 1.71Å

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