2rqr
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqr RCSB], [http://www.ebi.ac.uk/pdbsum/2rqr PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqr RCSB], [http://www.ebi.ac.uk/pdbsum/2rqr PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/ELMO1_HUMAN ELMO1_HUMAN]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.<ref>PMID:11595183</ref> <ref>PMID:12134158</ref> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Kigawa, T | + | [[Category: Kigawa, T]] |
- | [[Category: Koshiba, S | + | [[Category: Koshiba, S]] |
- | [[Category: Tochio, N | + | [[Category: Tochio, N]] |
- | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Cytoskeleton]] | [[Category: Cytoskeleton]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
- | [[Category: | + | [[Category: Structural genomic]] |
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Sh3 domain]] | [[Category: Sh3 domain]] | ||
[[Category: Sh3-binding]] | [[Category: Sh3-binding]] | ||
- | [[Category: Structural genomic]] |
Revision as of 11:24, 25 December 2014
The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex
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Categories: Homo sapiens | Kigawa, T | Koshiba, S | Tochio, N | Yokoyama, S | Apoptosis | Cytoskeleton | Guanine-nucleotide releasing factor | Kiaa0209 | Kiaa0281 | Membrane | National project on protein structural and functional analyse | Nppsfa | Phagocytosis | Phosphoprotein | Protein binding | Structural genomic | Rsgi | Sh3 domain | Sh3-binding