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4phk
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4phk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PHK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PHK FirstGlance]. <br> | <table><tr><td colspan='2'>[[4phk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PHK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PHK FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UB:(Z)-3-(4-CHLOROPHENYL)-2-MERCAPTOACRYLIC+ACID'>2UB</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UB:(Z)-3-(4-CHLOROPHENYL)-2-MERCAPTOACRYLIC+ACID'>2UB</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4phj|4phj]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4phj|4phj]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4phk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4phk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4phk RCSB], [http://www.ebi.ac.uk/pdbsum/4phk PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4phk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4phk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4phk RCSB], [http://www.ebi.ac.uk/pdbsum/4phk PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Adams, S E | + | [[Category: Adams, S E]] |
| - | [[Category: Allemann, R K | + | [[Category: Allemann, R K]] |
| - | [[Category: Hallett, M B | + | [[Category: Hallett, M B]] |
| - | [[Category: Miller, D J | + | [[Category: Miller, D J]] |
| - | [[Category: Rizkallah, P J | + | [[Category: Rizkallah, P J]] |
| - | [[Category: Robinson, E | + | [[Category: Robinson, E]] |
[[Category: Calcium binding]] | [[Category: Calcium binding]] | ||
[[Category: Domain vi]] | [[Category: Domain vi]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
Revision as of 11:28, 25 December 2014
The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids. The complex with (Z)-3-(4-chlorophenyl)-2-mercaptoacrylic acid
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