3i9k
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3i9k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I9K FirstGlance]. <br> | <table><tr><td colspan='2'>[[3i9k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I9K FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i9j|3i9j]], [[3i9l|3i9l]], [[3i9m|3i9m]], [[3i9n|3i9n]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i9j|3i9j]], [[3i9l|3i9l]], [[3i9m|3i9m]], [[3i9n|3i9n]]</td></tr> |
- | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i9k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i9k RCSB], [http://www.ebi.ac.uk/pdbsum/3i9k PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i9k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i9k RCSB], [http://www.ebi.ac.uk/pdbsum/3i9k PDBsum]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA]] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aplysia californica]] | [[Category: Aplysia californica]] | ||
- | [[Category: Graeff, R | + | [[Category: Graeff, R]] |
- | [[Category: Hao, Q | + | [[Category: Hao, Q]] |
- | [[Category: Jiang, H | + | [[Category: Jiang, H]] |
- | [[Category: Kriksunov, I A | + | [[Category: Kriksunov, I A]] |
- | [[Category: Lee, H C | + | [[Category: Lee, H C]] |
- | [[Category: Lin, H | + | [[Category: Lin, H]] |
- | [[Category: Liu, Q | + | [[Category: Liu, Q]] |
- | [[Category: Oppenheimer, N | + | [[Category: Oppenheimer, N]] |
- | [[Category: Potter, B V.L | + | [[Category: Potter, B V.L]] |
- | [[Category: Zhang, B | + | [[Category: Zhang, B]] |
[[Category: Adp-ribosyl cyclase]] | [[Category: Adp-ribosyl cyclase]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] |
Revision as of 11:35, 25 December 2014
Crystal structure of ADP ribosyl cyclase complexed with substrate NAD
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