4e68

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e68 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e68 RCSB], [http://www.ebi.ac.uk/pdbsum/4e68 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e68 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e68 RCSB], [http://www.ebi.ac.uk/pdbsum/4e68 PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/STAT3_MOUSE STAT3_MOUSE]] Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. STAT3B interacts with the N-terminal part of JUN to activate such promoters in a cooperative way.<ref>PMID:11294897</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 11:40, 25 December 2014

Unphosphorylated STAT3B core protein binding to dsDNA

4e68, resolution 2.58Å

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