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4co6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4co6]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CO6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4co6]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CO6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4co6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4co6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4co6 RCSB], [http://www.ebi.ac.uk/pdbsum/4co6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4co6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4co6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4co6 RCSB], [http://www.ebi.ac.uk/pdbsum/4co6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NCAP_NIPAV NCAP_NIPAV]] Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (By similarity). [[http://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV]] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Blackledge, M | + | [[Category: Blackledge, M]] |
| - | [[Category: Bourhis, J M | + | [[Category: Bourhis, J M]] |
| - | [[Category: Jamin, M | + | [[Category: Jamin, M]] |
| - | [[Category: Jensen, M R | + | [[Category: Jensen, M R]] |
| - | [[Category: Lawrence, P | + | [[Category: Lawrence, P]] |
| - | [[Category: Ruigrok, R W.H | + | [[Category: Ruigrok, R W.H]] |
| - | [[Category: Tarbouriech, N | + | [[Category: Tarbouriech, N]] |
| - | [[Category: Volchkov, V | + | [[Category: Volchkov, V]] |
| - | [[Category: Yabukarksi, F | + | [[Category: Yabukarksi, F]] |
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Paramyxovirus]] | [[Category: Paramyxovirus]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
[[Category: Viral replication]] | [[Category: Viral replication]] | ||
Revision as of 11:43, 25 December 2014
Crystal structure of the Nipah virus RNA free nucleoprotein- phosphoprotein complex
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