3pla
From Proteopedia
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| - | + | ==Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus== | |
| - | + | <StructureSection load='3pla' size='340' side='right' caption='[[3pla]], [[Resolution|resolution]] 3.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3pla]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PLA FirstGlance]. <br> |
| - | [[3pla]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLA OCA]. | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), rpl7ae, Ssol_1068 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pla RCSB], [http://www.ebi.ac.uk/pdbsum/3pla PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref> [[http://www.uniprot.org/uniprot/D0KRE2_SULS9 D0KRE2_SULS9]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.[HAMAP-Rule:MF_00326] | ||
==See Also== | ==See Also== | ||
*[[Kink-turn motif|Kink-turn motif]] | *[[Kink-turn motif|Kink-turn motif]] | ||
*[[Ribosomal protein L7|Ribosomal protein L7]] | *[[Ribosomal protein L7|Ribosomal protein L7]] | ||
| - | *[[Sandbox3pla|Sandbox3pla]] | ||
*[[User:Wayne Decatur/NASCE2011|User:Wayne Decatur/NASCE2011]] | *[[User:Wayne Decatur/NASCE2011|User:Wayne Decatur/NASCE2011]] | ||
*[[User:Wayne Decatur/UNH CME Workshop March 11 2011|User:Wayne Decatur/UNH CME Workshop March 11 2011]] | *[[User:Wayne Decatur/UNH CME Workshop March 11 2011|User:Wayne Decatur/UNH CME Workshop March 11 2011]] | ||
*[[User:Wayne Decatur/UNH Seminar Feb 1st 2011|User:Wayne Decatur/UNH Seminar Feb 1st 2011]] | *[[User:Wayne Decatur/UNH Seminar Feb 1st 2011|User:Wayne Decatur/UNH Seminar Feb 1st 2011]] | ||
*[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]] | *[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Sulfolobus solfataricus]] | [[Category: Sulfolobus solfataricus]] | ||
| - | [[Category: Jia, R | + | [[Category: Jia, R]] |
| - | [[Category: Lai, S | + | [[Category: Lai, S]] |
| - | [[Category: Lin, J | + | [[Category: Lin, J]] |
| - | [[Category: Lu, J | + | [[Category: Lu, J]] |
| - | [[Category: Xu, A | + | [[Category: Xu, A]] |
| - | [[Category: Ye, K | + | [[Category: Ye, K]] |
| - | [[Category: Zhang, L | + | [[Category: Zhang, L]] |
[[Category: Box c/d rna]] | [[Category: Box c/d rna]] | ||
[[Category: Guide rna]] | [[Category: Guide rna]] | ||
Revision as of 11:46, 25 December 2014
Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus
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Categories: Sulfolobus solfataricus | Jia, R | Lai, S | Lin, J | Lu, J | Xu, A | Ye, K | Zhang, L | Box c/d rna | Guide rna | Methyltransferase | Rna-binding | Rna-protein complex | Sam | Transferase-rna complex
