2ykf
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ykf' size='340' side='right' caption='[[2ykf]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2ykf' size='340' side='right' caption='[[2ykf]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ykf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YKF OCA]. <br> | + | <table><tr><td colspan='2'>[[2ykf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YKF FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ykh|2ykh]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ykh|2ykh]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ykf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ykf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ykf RCSB], [http://www.ebi.ac.uk/pdbsum/2ykf PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ykf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ykf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ykf RCSB], [http://www.ebi.ac.uk/pdbsum/2ykf PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PDTAS_MYCTU PDTAS_MYCTU]] Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The sensor region of the ubiquitous cytosolic sensor kinase, PdtaS, contains PAS and GAF domain sensing modules.,Preu J, Panjikar S, Morth P, Jaiswal R, Karunakar P, Tucker PA J Struct Biol. 2012 Feb;177(2):498-505. Epub 2011 Nov 17. PMID:22115998<ref>PMID:22115998</ref> | The sensor region of the ubiquitous cytosolic sensor kinase, PdtaS, contains PAS and GAF domain sensing modules.,Preu J, Panjikar S, Morth P, Jaiswal R, Karunakar P, Tucker PA J Struct Biol. 2012 Feb;177(2):498-505. Epub 2011 Nov 17. PMID:22115998<ref>PMID:22115998</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
| Line 22: | Line 24: | ||
[[Category: Histidine kinase]] | [[Category: Histidine kinase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Jaiswal, R | + | [[Category: Jaiswal, R]] |
| - | [[Category: Karunakar, P | + | [[Category: Karunakar, P]] |
| - | [[Category: Morth, P | + | [[Category: Morth, P]] |
| - | [[Category: Panjikar, S | + | [[Category: Panjikar, S]] |
| - | [[Category: Preu, J | + | [[Category: Preu, J]] |
| - | [[Category: Tucker, P A | + | [[Category: Tucker, P A]] |
[[Category: Gaf domain]] | [[Category: Gaf domain]] | ||
[[Category: Pas domain]] | [[Category: Pas domain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Two-component system]] | [[Category: Two-component system]] | ||
Revision as of 11:52, 25 December 2014
Sensor region of a sensor histidine kinase
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