2at5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2at5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AT5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2at5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AT5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDE:FE(III)+DEUTEROPORPHYRIN+IX'>FDE</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDE:FE(III)+DEUTEROPORPHYRIN+IX'>FDE</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2at4|2at4]], [[2at6|2at6]], [[2at8|2at8]], [[1ywb|1ywb]], [[1x8o|1x8o]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2at4|2at4]], [[2at6|2at6]], [[2at8|2at8]], [[1ywb|1ywb]], [[1x8o|1x8o]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2at5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2at5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2at5 RCSB], [http://www.ebi.ac.uk/pdbsum/2at5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2at5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2at5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2at5 RCSB], [http://www.ebi.ac.uk/pdbsum/2at5 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Rhodnius prolixus]]
[[Category: Rhodnius prolixus]]
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[[Category: Amoia, A M.]]
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[[Category: Amoia, A M]]
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[[Category: Montfort, W R.]]
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[[Category: Montfort, W R]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Ferrous]]
[[Category: Ferrous]]

Revision as of 11:54, 25 December 2014

1.22 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Containing Fe(III) Deuteroporphyrin IX Complexed With Nitric Oxide at pH 5.6

2at5, resolution 1.22Å

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