4my6

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4my6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4my6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4my6 RCSB], [http://www.ebi.ac.uk/pdbsum/4my6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4my6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4my6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4my6 RCSB], [http://www.ebi.ac.uk/pdbsum/4my6 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ENAH_HUMAN ENAH_HUMAN]] Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity).<ref>PMID:11696321</ref> <ref>PMID:18158903</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Barone, M.]]
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[[Category: Barone, M]]
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[[Category: Kuehne, R.]]
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[[Category: Kuehne, R]]
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[[Category: Roske, Y.]]
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[[Category: Roske, Y]]
[[Category: Actin dynamic]]
[[Category: Actin dynamic]]
[[Category: Cell adhesion-inhibitor complex]]
[[Category: Cell adhesion-inhibitor complex]]
[[Category: Molecular recognition]]
[[Category: Molecular recognition]]

Revision as of 12:09, 25 December 2014

EnaH-EVH1 domain in complex with non-peptidic low-molecular weight competitor

4my6, resolution 1.70Å

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