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3tck
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3tck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCK FirstGlance]. <br> | <table><tr><td colspan='2'>[[3tck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCK FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tcn|3tcn]], [[2z2i|2z2i]], [[2z2j|2z2j]], [[2z2k|2z2k]], [[2pth|2pth]], [[2jrc|2jrc]], [[3p2j|3p2j]], [[3td2|3td2]], [[3td6|3td6]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tcn|3tcn]], [[2z2i|2z2i]], [[2z2j|2z2j]], [[2z2k|2z2k]], [[2pth|2pth]], [[2jrc|2jrc]], [[3p2j|3p2j]], [[3td2|3td2]], [[3td6|3td6]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT1042, MTCY10G2.35, pth, Rv1014c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT1042, MTCY10G2.35, pth, Rv1014c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tck OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tck RCSB], [http://www.ebi.ac.uk/pdbsum/3tck PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tck OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tck RCSB], [http://www.ebi.ac.uk/pdbsum/3tck PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PTH_MYCTU PTH_MYCTU]] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.,Selvaraj M, Ahmad R, Varshney U, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt, 2):124-8. Epub 2012 Jan 21. PMID:22297982<ref>PMID:22297982</ref> | Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.,Selvaraj M, Ahmad R, Varshney U, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt, 2):124-8. Epub 2012 Jan 21. PMID:22297982<ref>PMID:22297982</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
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[[Category: Aminoacyl-tRNA hydrolase]] | [[Category: Aminoacyl-tRNA hydrolase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Ahmad, R | + | [[Category: Ahmad, R]] |
| - | [[Category: Selvaraj, M | + | [[Category: Selvaraj, M]] |
| - | [[Category: Varshney, U | + | [[Category: Varshney, U]] |
| - | [[Category: Vijayan, M | + | [[Category: Vijayan, M]] |
[[Category: Cytosol]] | [[Category: Cytosol]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 12:17, 25 December 2014
Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis - Form 4
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