1lk0

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1lk0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LK0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1lk0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LK0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ljl|1ljl]], [[1lju|1lju]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ljl|1ljl]], [[1lju|1lju]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">arsc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">arsc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arsenate_reductase_(glutaredoxin) Arsenate reductase (glutaredoxin)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.20.4.1 1.20.4.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arsenate_reductase_(glutaredoxin) Arsenate reductase (glutaredoxin)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.20.4.1 1.20.4.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lk0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lk0 RCSB], [http://www.ebi.ac.uk/pdbsum/1lk0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lk0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lk0 RCSB], [http://www.ebi.ac.uk/pdbsum/1lk0 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ARSC_STAAU ARSC_STAAU]] Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances.[HAMAP-Rule:MF_01624]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Belle, K Van.]]
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[[Category: Belle, K Van]]
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[[Category: Brosens, E.]]
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[[Category: Brosens, E]]
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[[Category: Desmyter, A.]]
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[[Category: Desmyter, A]]
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[[Category: Gieter, M De.]]
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[[Category: Gieter, M De]]
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[[Category: Martins, J C.]]
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[[Category: Martins, J C]]
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[[Category: Messens, J.]]
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[[Category: Messens, J]]
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[[Category: Wieruszeski, J M.]]
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[[Category: Wieruszeski, J M]]
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[[Category: Willem, R.]]
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[[Category: Willem, R]]
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[[Category: Wyns, L.]]
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[[Category: Wyns, L]]
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[[Category: Zegers, I.]]
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[[Category: Zegers, I]]
[[Category: Disulfide cascade]]
[[Category: Disulfide cascade]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: P-loop]]
[[Category: P-loop]]
[[Category: Ptpase i fold]]
[[Category: Ptpase i fold]]

Revision as of 12:18, 25 December 2014

Disulfide intermediate of C89L Arsenate reductase from pI258

1lk0, resolution 1.60Å

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