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1lio

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1lio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1dh2 1dh2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LIO FirstGlance]. <br>
<table><tr><td colspan='2'>[[1lio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1dh2 1dh2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LIO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lii|1lii]], [[1lij|1lij]], [[1lik|1lik]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lii|1lii]], [[1lij|1lij]], [[1lik|1lik]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lio RCSB], [http://www.ebi.ac.uk/pdbsum/1lio PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lio RCSB], [http://www.ebi.ac.uk/pdbsum/1lio PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ADK_TOXGO ADK_TOXGO]] ATP-dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. It is a key purine metabolic enzyme in the opportunistic parasitic protozoan toxoplasma gondii as it cannot synthesize purines de novo.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Adenosine kinase]]
[[Category: Adenosine kinase]]
[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
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[[Category: Brennan, R G.]]
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[[Category: Brennan, R G]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick, S E]]
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[[Category: Mathews, I I.]]
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[[Category: Mathews, I I]]
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[[Category: Schumacher, M A.]]
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[[Category: Schumacher, M A]]
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[[Category: Scott, D M.]]
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[[Category: Scott, D M]]
[[Category: Alpha-beta structure]]
[[Category: Alpha-beta structure]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 12:32, 25 December 2014

STRUCTURE OF APO T. GONDII ADENOSINE KINASE

1lio, resolution 2.50Å

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