2f4a

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f4a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F4A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F4A FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f4a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F4A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F4A FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=TOU:THIOUREA'>TOU</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=TOU:THIOUREA'>TOU</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f2n|2f2n]], [[2f30|2f30]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f2n|2f2n]], [[2f30|2f30]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f4a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f4a RCSB], [http://www.ebi.ac.uk/pdbsum/2f4a PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f4a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f4a RCSB], [http://www.ebi.ac.uk/pdbsum/2f4a PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
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[[Category: Prange, T.]]
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[[Category: Prange, T]]
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[[Category: Salem, M.]]
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[[Category: Salem, M]]
[[Category: Barnase]]
[[Category: Barnase]]
[[Category: Bromoethanol]]
[[Category: Bromoethanol]]
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[[Category: Glutaraldehyde]]
[[Category: Glutaraldehyde]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Lysozyme]]
 
[[Category: Thiourea]]
[[Category: Thiourea]]
[[Category: Urea]]
[[Category: Urea]]

Revision as of 12:33, 25 December 2014

Triclinic cross-linked lysozyme soaked with thiourea 1.5M

2f4a, resolution 1.95Å

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