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1qqr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1qqr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_dysgalactiae_subsp._equisimilis Streptococcus dysgalactiae subsp. equisimilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QQR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1qqr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_dysgalactiae_subsp._equisimilis Streptococcus dysgalactiae subsp. equisimilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QQR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qqr RCSB], [http://www.ebi.ac.uk/pdbsum/1qqr PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qqr RCSB], [http://www.ebi.ac.uk/pdbsum/1qqr PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/STRP_STREQ STRP_STREQ]] This protein is not a protease, but it activates plasminogen by complexing with it. As a potential virulence factor, it is thought to prevent the formation of effective fibrin barriers around the site of infection, thereby contributing to the invasiveness of the cells.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Streptococcus dysgalactiae subsp. equisimilis]]
[[Category: Streptococcus dysgalactiae subsp. equisimilis]]
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[[Category: Dobson, C.]]
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[[Category: Dobson, C]]
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[[Category: Fox, V F.]]
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[[Category: Fox, V F]]
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[[Category: Jones, E Y.]]
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[[Category: Jones, E Y]]
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[[Category: Phillips, C.]]
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[[Category: Phillips, C]]
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[[Category: Ponting, C P.]]
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[[Category: Ponting, C P]]
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[[Category: Smith, R A.G.]]
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[[Category: Smith, R A.G]]
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[[Category: Spraggon, G.]]
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[[Category: Spraggon, G]]
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[[Category: Stuart, D I.]]
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[[Category: Stuart, D I]]
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[[Category: Zhang, X X.]]
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[[Category: Zhang, X X]]
[[Category: Fibrinolysis]]
[[Category: Fibrinolysis]]
[[Category: Hydrolase activator]]
[[Category: Hydrolase activator]]
[[Category: Non-proteolytic]]
[[Category: Non-proteolytic]]
[[Category: Plasminogen activation]]
[[Category: Plasminogen activation]]

Revision as of 12:33, 25 December 2014

CRYSTAL STRUCTURE OF STREPTOKINASE DOMAIN B

1qqr, resolution 2.30Å

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