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2iou

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iou]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bordetella_bronchiseptica_rb50 Bordetella bronchiseptica rb50] and [http://en.wikipedia.org/wiki/Bordetella_phage_bpp-1 Bordetella phage bpp-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IOU FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iou]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bordetella_bronchiseptica_rb50 Bordetella bronchiseptica rb50] and [http://en.wikipedia.org/wiki/Bordetella_phage_bpp-1 Bordetella phage bpp-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IOU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yu0|1yu0]], [[1dab|1dab]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yu0|1yu0]], [[1dab|1dab]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mtd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=194699 Bordetella phage BPP-1]), Prn ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=257310 Bordetella bronchiseptica RB50])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mtd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=194699 Bordetella phage BPP-1]), Prn ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=257310 Bordetella bronchiseptica RB50])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iou OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iou RCSB], [http://www.ebi.ac.uk/pdbsum/2iou PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iou OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iou RCSB], [http://www.ebi.ac.uk/pdbsum/2iou PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PERT_BORBR PERT_BORBR]] Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bordetella bronchiseptica rb50]]
[[Category: Bordetella bronchiseptica rb50]]
[[Category: Bordetella phage bpp-1]]
[[Category: Bordetella phage bpp-1]]
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[[Category: Ghosh, P.]]
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[[Category: Ghosh, P]]
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[[Category: Miller, J L.]]
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[[Category: Miller, J L]]
[[Category: Mtd]]
[[Category: Mtd]]
[[Category: Pertactin]]
[[Category: Pertactin]]
[[Category: Prn]]
[[Category: Prn]]
[[Category: Viral protein-membrane protein complex]]
[[Category: Viral protein-membrane protein complex]]

Revision as of 12:35, 25 December 2014

Major Tropism Determinant P1 (Mtd-P1) Variant Complexed with Bordetella brochiseptica Virulence Factor Pertactin extracellular domain (Prn-E).

2iou, resolution 3.16Å

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