2gf0

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf0 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN]] Displays low GTPase activity and exist predominantly in the GTP-bound form.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith, C]]
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[[Category: Bray, J.]]
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[[Category: Bray, J]]
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[[Category: Delft, F von.]]
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[[Category: Delft, F von]]
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[[Category: Doyle, D.]]
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[[Category: Doyle, D]]
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[[Category: Edwards, A.]]
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[[Category: Edwards, A]]
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[[Category: Elkins, J.]]
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[[Category: Elkins, J]]
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[[Category: Fedorov, O.]]
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[[Category: Fedorov, O]]
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[[Category: Gileadi, O.]]
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[[Category: Gileadi, O]]
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[[Category: Niesen, F E.]]
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[[Category: Niesen, F E]]
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[[Category: Papagrigoriou, E.]]
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[[Category: Papagrigoriou, E]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Salah, E.]]
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[[Category: Salah, E]]
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[[Category: Schoch, G.]]
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[[Category: Schoch, G]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom, M]]
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[[Category: Turnbull, A P.]]
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[[Category: Turnbull, A P]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Wen-Hwa, L.]]
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[[Category: Wen-Hwa, L]]
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[[Category: Yang, X.]]
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[[Category: Yang, X]]
[[Category: Dira]]
[[Category: Dira]]
[[Category: Gdp/gtp binding]]
[[Category: Gdp/gtp binding]]
[[Category: Gtp hydrolysis]]
[[Category: Gtp hydrolysis]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 
[[Category: Transport protein]]
[[Category: Transport protein]]

Revision as of 12:40, 25 December 2014

The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state

2gf0, resolution 1.90Å

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