3rye
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rye OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rye RCSB], [http://www.ebi.ac.uk/pdbsum/3rye PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rye OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rye RCSB], [http://www.ebi.ac.uk/pdbsum/3rye PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. | ||
==See Also== | ==See Also== | ||
Revision as of 12:49, 25 December 2014
Human FDPS Synthase in Complex with a N-Methyl Pyridinum Bisphosphonate
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