3mva

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mva RCSB], [http://www.ebi.ac.uk/pdbsum/3mva PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mva RCSB], [http://www.ebi.ac.uk/pdbsum/3mva PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MTERF_HUMAN MTERF_HUMAN]] Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.<ref>PMID:20550934</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 12:51, 25 December 2014

Crystal structure of human MTERF1 bound to the termination sequence

3mva, resolution 2.20Å

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