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2ce3
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ce3]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CE3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ce3]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CE3 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c8t|2c8t]], [[2cby|2cby]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c8t|2c8t]], [[2cby|2cby]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ce3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ce3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ce3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ce3 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ce3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ce3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ce3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ce3 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CLPP1_MYCTU CLPP1_MYCTU]] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Clp Protease|Clp Protease]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Alzari, P M | + | [[Category: Alzari, P M]] |
| - | [[Category: Kim, C Y | + | [[Category: Kim, C Y]] |
| - | [[Category: Lekin, T | + | [[Category: Lekin, T]] |
| - | [[Category: Ortiz-Lombardia, M | + | [[Category: Ortiz-Lombardia, M]] |
| - | [[Category: Segelke, B | + | [[Category: Segelke, B]] |
[[Category: Atp-dependent protease]] | [[Category: Atp-dependent protease]] | ||
[[Category: Clp protease]] | [[Category: Clp protease]] | ||
[[Category: Endopeptidase]] | [[Category: Endopeptidase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Proteolytic subunit]] | [[Category: Proteolytic subunit]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 12:51, 25 December 2014
CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS
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