3br5

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3br5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3br5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3br5 RCSB], [http://www.ebi.ac.uk/pdbsum/3br5 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3br5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3br5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3br5 RCSB], [http://www.ebi.ac.uk/pdbsum/3br5 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/QACR_STAAM QACR_STAAM]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brooks, B E.]]
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[[Category: Brooks, B E]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Multidrug resistance]]
[[Category: Multidrug resistance]]

Revision as of 12:53, 25 December 2014

Crystal Structure of the Complex of Rhodamine 6G Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor

3br5, resolution 2.90Å

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