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1v5b
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1v5b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_coagulans Bacillus coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V5B FirstGlance]. <br> | <table><tr><td colspan='2'>[[1v5b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_coagulans Bacillus coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V5B FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v5b RCSB], [http://www.ebi.ac.uk/pdbsum/1v5b PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v5b RCSB], [http://www.ebi.ac.uk/pdbsum/1v5b PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEU3_BACCO LEU3_BACCO]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: 3-isopropylmalate dehydrogenase]] | [[Category: 3-isopropylmalate dehydrogenase]] | ||
[[Category: Bacillus coagulans]] | [[Category: Bacillus coagulans]] | ||
| - | [[Category: Fujita, K | + | [[Category: Fujita, K]] |
| - | [[Category: Minami, H | + | [[Category: Minami, H]] |
| - | [[Category: Mizui, R | + | [[Category: Mizui, R]] |
| - | [[Category: Nakamura, S | + | [[Category: Nakamura, S]] |
| - | [[Category: Sekiguchi, T | + | [[Category: Sekiguchi, T]] |
| - | [[Category: Suzuki, K | + | [[Category: Suzuki, K]] |
| - | [[Category: Takenaka, A | + | [[Category: Takenaka, A]] |
| - | [[Category: Tsunoda, M | + | [[Category: Tsunoda, M]] |
| - | [[Category: Tsuzaki, S | + | [[Category: Tsuzaki, S]] |
[[Category: Bacillus coagulan]] | [[Category: Bacillus coagulan]] | ||
[[Category: Homo dimer]] | [[Category: Homo dimer]] | ||
Revision as of 12:54, 25 December 2014
The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans
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