4g29
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g29 RCSB], [http://www.ebi.ac.uk/pdbsum/4g29 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g29 RCSB], [http://www.ebi.ac.uk/pdbsum/4g29 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SSEI_SALTY SSEI_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required to maintain a long-term chronic systemic infection in mice. It inhibits normal cell migration of primary macrophages and dendritic cells, by a mechanism that involves interaction with the host factor IQGAP1, an important regulator of the cytoskeleton and cell migration. Also accelerates the systemic spread of infection from the gastrointestinal tract to the bloodstream, probably by interacting with host TRIP6.<ref>PMID:17095609</ref> <ref>PMID:19956712</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 13:17, 25 December 2014
Structure of the Catalytic Domain of the Salmonella Virulence Factor SseI
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