4b6h
From Proteopedia
(Difference between revisions)
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6h RCSB], [http://www.ebi.ac.uk/pdbsum/4b6h PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6h RCSB], [http://www.ebi.ac.uk/pdbsum/4b6h PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DCP1A_HUMAN DCP1A_HUMAN]] Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.<ref>PMID:11836524</ref> <ref>PMID:12417715</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 13:26, 25 December 2014
Structure of hDcp1a in complex with proline rich sequence of PNRC2
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