2euk

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2euk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EUK FirstGlance]. <br>
<table><tr><td colspan='2'>[[2euk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EUK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NER:(15E)-TETRACOS-15-ENOIC+ACID'>NER</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NER:(15E)-TETRACOS-15-ENOIC+ACID'>NER</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1swx|1swx]], [[1sx6|1sx6]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1swx|1swx]], [[1sx6|1sx6]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2euk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2euk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2euk RCSB], [http://www.ebi.ac.uk/pdbsum/2euk PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2euk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2euk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2euk RCSB], [http://www.ebi.ac.uk/pdbsum/2euk PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Abagyan, R.]]
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[[Category: Abagyan, R]]
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[[Category: Brown, R E.]]
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[[Category: Brown, R E]]
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[[Category: Kanack, A T.]]
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[[Category: Kanack, A T]]
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[[Category: Malakhova, M L.]]
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[[Category: Malakhova, M L]]
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[[Category: Malinina, L.]]
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[[Category: Malinina, L]]
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[[Category: Patel, D J.]]
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[[Category: Patel, D J]]
[[Category: Lipid transport]]
[[Category: Lipid transport]]
[[Category: Protein-glycolipid complex]]
[[Category: Protein-glycolipid complex]]

Revision as of 13:37, 25 December 2014

Crystal Structure of Human Glycolipid Transfer Protein complexed with 24:1 Galactosylceramide

2euk, resolution 1.85Å

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