3acl

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3acl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3acl RCSB], [http://www.ebi.ac.uk/pdbsum/3acl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3acl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3acl RCSB], [http://www.ebi.ac.uk/pdbsum/3acl PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN]] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Miyazaki, I.]]
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[[Category: Miyazaki, I]]
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[[Category: Okumura, H.]]
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[[Category: Okumura, H]]
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[[Category: Osada, H.]]
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[[Category: Osada, H]]
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[[Category: Simizu, S.]]
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[[Category: Simizu, S]]
[[Category: Complex]]
[[Category: Complex]]
[[Category: Cupin]]
[[Category: Cupin]]

Revision as of 13:38, 25 December 2014

Crystal Structure of Human Pirin in complex with Triphenyl Compound

3acl, resolution 2.35Å

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