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3d81
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d81 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d81 RCSB], [http://www.ebi.ac.uk/pdbsum/3d81 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d81 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d81 RCSB], [http://www.ebi.ac.uk/pdbsum/3d81 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NPD_THEMA NPD_THEMA]] NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP-ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear.<ref>PMID:17684016</ref> <ref>PMID:16905097</ref> <ref>PMID:19801667</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 13:43, 25 December 2014
Sir2-S-alkylamidate complex crystal structure
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