3uc4
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3uc4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UC4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3uc4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UC4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uc3|3uc3]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uc3|3uc3]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SRK2E, OST1, SNRK2.6, At4g33950, F17I5.140 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SRK2E, OST1, SNRK2.6, At4g33950, F17I5.140 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uc4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3uc4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uc4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3uc4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SRK2E_ARATH SRK2E_ARATH]] Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS).<ref>PMID:12468729</ref> <ref>PMID:12514244</ref> <ref>PMID:12047634</ref> <ref>PMID:15064385</ref> <ref>PMID:16959575</ref> <ref>PMID:16682349</ref> <ref>PMID:16365038</ref> <ref>PMID:16766677</ref> <ref>PMID:17307925</ref> <ref>PMID:19955427</ref> <ref>PMID:19955405</ref> <ref>PMID:20128877</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.,Ng LM, Soon FF, Zhou XE, West GM, Kovach A, Suino-Powell KM, Chalmers MJ, Li J, Yong EL, Zhu JK, Griffin PR, Melcher K, Xu HE Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21259-64. Epub 2011 Dec 12. PMID:22160701<ref>PMID:22160701</ref> | Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.,Ng LM, Soon FF, Zhou XE, West GM, Kovach A, Suino-Powell KM, Chalmers MJ, Li J, Yong EL, Zhu JK, Griffin PR, Melcher K, Xu HE Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21259-64. Epub 2011 Dec 12. PMID:22160701<ref>PMID:22160701</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
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[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Kovach, A | + | [[Category: Kovach, A]] |
| - | [[Category: Li, J | + | [[Category: Li, J]] |
| - | [[Category: Melcher, K | + | [[Category: Melcher, K]] |
| - | [[Category: Ng, L M | + | [[Category: Ng, L M]] |
| - | [[Category: Soon, F F | + | [[Category: Soon, F F]] |
| - | [[Category: Suino-Powell, K M | + | [[Category: Suino-Powell, K M]] |
| - | [[Category: Xu, H E | + | [[Category: Xu, H E]] |
| - | [[Category: Zhou, X E | + | [[Category: Zhou, X E]] |
[[Category: Aba signaling]] | [[Category: Aba signaling]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Snrk2 6]] | [[Category: Snrk2 6]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 13:48, 25 December 2014
The crystal structure of Snf1-related kinase 2.6
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