2yup

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yup]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YUP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yup]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YUP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SORBS3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SORBS3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yup OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yup RCSB], [http://www.ebi.ac.uk/pdbsum/2yup PDBsum], [http://www.topsan.org/Proteins/RSGI/2yup TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yup OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yup RCSB], [http://www.ebi.ac.uk/pdbsum/2yup PDBsum], [http://www.topsan.org/Proteins/RSGI/2yup TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/VINEX_HUMAN VINEX_HUMAN]] Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Abe, H.]]
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[[Category: Abe, H]]
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[[Category: Inoue, M.]]
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[[Category: Inoue, M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba, S]]
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[[Category: Miyamoto, K.]]
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[[Category: Miyamoto, K]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Saito, K.]]
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[[Category: Saito, K]]
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[[Category: Sasagawa, A.]]
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[[Category: Sasagawa, A]]
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[[Category: Tochio, N.]]
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[[Category: Tochio, N]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Scam-1]]
[[Category: Scam-1]]
[[Category: Sh3-containing adapter molecule 1]]
[[Category: Sh3-containing adapter molecule 1]]
[[Category: Sorbin and sh3 domain-containing protein 3]]
[[Category: Sorbin and sh3 domain-containing protein 3]]
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[[Category: Structural genomic]]
 

Revision as of 13:53, 25 December 2014

Solution structure of the second SH3 domain of human Vinexin

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