2ywk
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ywk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YWK FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ywk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YWK FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ywk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ywk RCSB], [http://www.ebi.ac.uk/pdbsum/2ywk PDBsum], [http://www.topsan.org/Proteins/RSGI/2ywk TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ywk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ywk RCSB], [http://www.ebi.ac.uk/pdbsum/2ywk PDBsum], [http://www.topsan.org/Proteins/RSGI/2ywk TOPSAN]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/RBM11_HUMAN RBM11_HUMAN]] Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.<ref>PMID:21984414</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Kaminishi, T | + | [[Category: Kaminishi, T]] |
- | [[Category: Kawazoe, M | + | [[Category: Kawazoe, M]] |
- | [[Category: Morita, S | + | [[Category: Morita, S]] |
- | [[Category: Nishino, A | + | [[Category: Nishino, A]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Shirouzu, M | + | [[Category: Shirouzu, M]] |
- | [[Category: Takemoto, C | + | [[Category: Takemoto, C]] |
- | [[Category: Terada, T | + | [[Category: Terada, T]] |
- | [[Category: Uchikubo-Kamo, T | + | [[Category: Uchikubo-Kamo, T]] |
- | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
- | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Rrm-domain]] | [[Category: Rrm-domain]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
- | [[Category: Structural genomic]] |
Revision as of 14:06, 25 December 2014
Crystal structure of RRM-domain derived from human putative RNA-binding protein 11
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Categories: Homo sapiens | Kaminishi, T | Kawazoe, M | Morita, S | Nishino, A | Structural genomic | Shirouzu, M | Takemoto, C | Terada, T | Uchikubo-Kamo, T | Yokoyama, S | National project on protein structural and functional analyse | Nppsfa | Rna binding protein | Rna-binding | Rrm-domain | Rsgi