3hot

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hot RCSB], [http://www.ebi.ac.uk/pdbsum/3hot PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hot RCSB], [http://www.ebi.ac.uk/pdbsum/3hot PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 14:08, 25 December 2014

Crystal structure of the Mos1 mariner paired end complex with Mn

3hot, resolution 3.25Å

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