3ngo
From Proteopedia
(Difference between revisions)
Line 8: | Line 8: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ngo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ngo RCSB], [http://www.ebi.ac.uk/pdbsum/3ngo PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ngo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ngo RCSB], [http://www.ebi.ac.uk/pdbsum/3ngo PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CNO6L_HUMAN CNO6L_HUMAN]] Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA.<ref>PMID:17452450</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 26: | Line 28: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Ribonuclease|Ribonuclease]] | ||
+ | *[[Temp|Temp]] | ||
== References == | == References == | ||
<references/> | <references/> |
Revision as of 14:12, 25 December 2014
Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA
|