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1dfc
From Proteopedia
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dfc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dfc RCSB], [http://www.ebi.ac.uk/pdbsum/1dfc PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1dfc TOPSAN]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dfc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dfc RCSB], [http://www.ebi.ac.uk/pdbsum/1dfc PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1dfc TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FSCN1_HUMAN FSCN1_HUMAN]] Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.<ref>PMID:9362073</ref> <ref>PMID:9571235</ref> <ref>PMID:20137952</ref> <ref>PMID:20393565</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 14:24, 25 December 2014
CRYSTAL STRUCTURE OF HUMAN FASCIN, AN ACTIN-CROSSLINKING PROTEIN
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