2mjp

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b78|1b78]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b78|1b78]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjp RCSB], [http://www.ebi.ac.uk/pdbsum/2mjp PDBsum], [http://www.topsan.org/Proteins/BSGC/2mjp TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjp RCSB], [http://www.ebi.ac.uk/pdbsum/2mjp PDBsum], [http://www.topsan.org/Proteins/BSGC/2mjp TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NTPA_METJA NTPA_METJA]] Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective monophosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions.<ref>PMID:10404228</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Structural genomic]]
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[[Category: Cho, Y.]]
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[[Category: Cho, Y]]
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[[Category: Chung, J H.]]
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[[Category: Chung, J H]]
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[[Category: Han, Y S.]]
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[[Category: Han, Y S]]
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[[Category: Hwang, K Y.]]
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[[Category: Hwang, K Y]]
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[[Category: Kim, S H.]]
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[[Category: Kim, S H]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
[[Category: Bsgc structure funded by nih]]
[[Category: Hyperthermal protein]]
[[Category: Hyperthermal protein]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyrophosphatase]]
[[Category: Pyrophosphatase]]
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[[Category: Structural genomic]]
 

Revision as of 14:26, 25 December 2014

STRUCTURE-BASED IDENTIFICATION OF THE BIOCHEMICAL FUNCTION OF A HYPOTHETICAL PROTEIN FROM METHANOCOCCUS JANNASCHII:MJ0226

2mjp, resolution 2.20Å

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