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3w4y
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w4y RCSB], [http://www.ebi.ac.uk/pdbsum/3w4y PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w4y RCSB], [http://www.ebi.ac.uk/pdbsum/3w4y PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ERV1_YEAST ERV1_YEAST]] FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space (IMS). Forms a redox cycle with MIA40 that involves a disulfide relay system. Important for maintaining the cysteine residues in MIA40 in an oxidized state. Reduced ERV1 is reoxidized by cytochrome c. Required for the maturation of cytoplasmic, but not of mitochondrial Fe/S proteins.[PROSITE-ProRule:PRU00654]<ref>PMID:10899311</ref> <ref>PMID:11493598</ref> <ref>PMID:12654008</ref> <ref>PMID:15989955</ref> <ref>PMID:16181637</ref> <ref>PMID:16185707</ref> | ||
==See Also== | ==See Also== | ||
*[[Sulfhydryl oxidase|Sulfhydryl oxidase]] | *[[Sulfhydryl oxidase|Sulfhydryl oxidase]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 14:26, 25 December 2014
Crystal structure of yeast Erv1 core
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Categories: Baker's yeast | Thiol oxidase | Endo, T | Kawano, S | Terao, K | Watanabe, N | Alpha helix | Disulfide bond | Mitochondria | Oxidoreductase | Redox | Tim40/mia40
