3rgu
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3rgu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_parasanguinis Streptococcus parasanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RGU FirstGlance]. <br> | <table><tr><td colspan='2'>[[3rgu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_parasanguinis Streptococcus parasanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RGU FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kub|2kub]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kub|2kub]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fap1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1318 Streptococcus parasanguinis])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fap1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1318 Streptococcus parasanguinis])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rgu RCSB], [http://www.ebi.ac.uk/pdbsum/3rgu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rgu RCSB], [http://www.ebi.ac.uk/pdbsum/3rgu PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q9ZFF9_STRPA Q9ZFF9_STRPA]] The major structural element of fimbriae. Required for adherence to saliva-coated hydroxyapatite beads (SHA), an in vitro tooth model. A Fap1-dependent increase in adherence is seen as the pH is reduced from pH 8 to pH 5.<ref>PMID:10594831</ref> <ref>PMID:9632253</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation.,Garnett JA, Simpson PJ, Taylor J, Benjamin SV, Tagliaferri C, Cota E, Chen YY, Wu H, Matthews S Biochem Biophys Res Commun. 2012 Jan 6;417(1):421-6. Epub 2011 Dec 7. PMID:22166217<ref>PMID:22166217</ref> | Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation.,Garnett JA, Simpson PJ, Taylor J, Benjamin SV, Tagliaferri C, Cota E, Chen YY, Wu H, Matthews S Biochem Biophys Res Commun. 2012 Jan 6;417(1):421-6. Epub 2011 Dec 7. PMID:22166217<ref>PMID:22166217</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptococcus parasanguinis]] | [[Category: Streptococcus parasanguinis]] | ||
| - | [[Category: Garnett, J A | + | [[Category: Garnett, J A]] |
| - | [[Category: Matthews, S J | + | [[Category: Matthews, S J]] |
[[Category: Adhesion]] | [[Category: Adhesion]] | ||
[[Category: Cell wall]] | [[Category: Cell wall]] | ||
Revision as of 14:30, 25 December 2014
Structure of Fap-NRa at pH 5.0
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