4ki7
From Proteopedia
(Difference between revisions)
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<StructureSection load='4ki7' size='340' side='right' caption='[[4ki7]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='4ki7' size='340' side='right' caption='[[4ki7]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ki7]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KI7 OCA]. <br> | + | <table><tr><td colspan='2'>[[4ki7]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KI7 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1R2:3-HYDROXY-5-(3-NITROPHENOXY)BENZOIC+ACID'>1R2</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1R2:3-HYDROXY-5-(3-NITROPHENOXY)BENZOIC+ACID'>1R2</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ki7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ki7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ki7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ki7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ki7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ki7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ki7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ki7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 3-dehydroquinate dehydratase]] | [[Category: 3-dehydroquinate dehydratase]] | ||
| - | [[Category: Abell, C | + | [[Category: Abell, C]] |
| - | [[Category: Blundell, T L | + | [[Category: Blundell, T L]] |
| - | [[Category: Dias, M V.B | + | [[Category: Dias, M V.B]] |
| - | [[Category: Howard, N G | + | [[Category: Howard, N G]] |
[[Category: Dehydratase]] | [[Category: Dehydratase]] | ||
[[Category: Dhqase]] | [[Category: Dhqase]] | ||
[[Category: Lyase-lyase inhibitor complex]] | [[Category: Lyase-lyase inhibitor complex]] | ||
Revision as of 14:44, 25 December 2014
Design and structural analysis of aromatic inhibitors of type II dehydroquinase from Mycobacterium tuberculosis - compound 41c [3-hydroxy-5-(3-nitrophenoxy)benzoic acid]
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