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2dw1

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[[Image:2dw1.jpg|left|200px]]<br /><applet load="2dw1" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2dw1.jpg|left|200px]]
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caption="2dw1, resolution 2.5&Aring;" />
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'''Crystal structure of VAP2 from Crotalus atrox venom (Form 2-2 crystal)'''<br />
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{{Structure
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|PDB= 2dw1 |SIZE=350|CAPTION= <scene name='initialview01'>2dw1</scene>, resolution 2.5&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=GM6:3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE'>GM6</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''Crystal structure of VAP2 from Crotalus atrox venom (Form 2-2 crystal)'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2DW1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=GM6:'>GM6</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DW1 OCA].
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2DW1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DW1 OCA].
==Reference==
==Reference==
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Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins., Igarashi T, Araki S, Mori H, Takeda S, FEBS Lett. 2007 May 29;581(13):2416-22. Epub 2007 Apr 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17485084 17485084]
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Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins., Igarashi T, Araki S, Mori H, Takeda S, FEBS Lett. 2007 May 29;581(13):2416-22. Epub 2007 Apr 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17485084 17485084]
[[Category: Crotalus atrox]]
[[Category: Crotalus atrox]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: svmp]]
[[Category: svmp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:03:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:32:17 2008''

Revision as of 14:32, 20 March 2008

Image:2dw1.jpg


PDB ID 2dw1

Drag the structure with the mouse to rotate
, resolution 2.5Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



Crystal structure of VAP2 from Crotalus atrox venom (Form 2-2 crystal)


Overview

Catrocollastatin/vascular apoptosis-inducing protein (VAP)2B is a metalloproteinase from Crotalus atrox venom, possessing metalloproteinase/disintegrin/cysteine-rich (MDC) domains that bear the typical domain architecture of a disintegrin and metalloproteinase (ADAM)/adamalysin/reprolysin family proteins. Here we describe crystal structures of catrocollastatin/VAP2B in three different crystal forms, representing the first reported crystal structures of a member of the monomeric class of this family of proteins. The overall structures show good agreement with both monomers of atypical homodimeric VAP1. Comparison of the six catrocollastatin/VAP2B monomer structures and the structures of VAP1 reveals a dynamic, modular architecture that may be important for the functions of ADAM/adamalysin/reprolysin family proteins.

About this Structure

2DW1 is a Single protein structure of sequence from Crotalus atrox. Full crystallographic information is available from OCA.

Reference

Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins., Igarashi T, Araki S, Mori H, Takeda S, FEBS Lett. 2007 May 29;581(13):2416-22. Epub 2007 Apr 30. PMID:17485084

Page seeded by OCA on Thu Mar 20 16:32:17 2008

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