1j3c

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3C FirstGlance]. <br>
<table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3C FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [http://www.ebi.ac.uk/pdbsum/1j3c PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [http://www.ebi.ac.uk/pdbsum/1j3c PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/HMGB2_PIG HMGB2_PIG]] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Kurita, J.]]
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[[Category: Kurita, J]]
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[[Category: Shimahara, H.]]
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[[Category: Shimahara, H]]
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[[Category: Tate, S.]]
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[[Category: Tate, S]]
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[[Category: Yoshida, M.]]
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[[Category: Yoshida, M]]
[[Category: Dna binding protein]]
[[Category: Dna binding protein]]
[[Category: Hmg-box]]
[[Category: Hmg-box]]

Revision as of 14:47, 25 December 2014

Solution structure of the C-terminal domain of the HMGB2

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