4c8r
From Proteopedia
(Difference between revisions)
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<StructureSection load='4c8r' size='340' side='right' caption='[[4c8r]], [[Resolution|resolution]] 2.82Å' scene=''> | <StructureSection load='4c8r' size='340' side='right' caption='[[4c8r]], [[Resolution|resolution]] 2.82Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4c8r]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8R OCA]. <br> | + | <table><tr><td colspan='2'>[[4c8r]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8R FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6YT:N-(3-HYDROXYPICOLINOYL)-S-(PYRIDIN-2-YLMETHYL)-L-CYSTEINE'>6YT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6YT:N-(3-HYDROXYPICOLINOYL)-S-(PYRIDIN-2-YLMETHYL)-L-CYSTEINE'>6YT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-butyrobetaine_dioxygenase Gamma-butyrobetaine dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.1 1.14.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8r RCSB], [http://www.ebi.ac.uk/pdbsum/4c8r PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8r RCSB], [http://www.ebi.ac.uk/pdbsum/4c8r PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BODG_HUMAN BODG_HUMAN]] Catalyzes the formation of L-carnitine from gamma-butyrobetaine. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Gamma-butyrobetaine dioxygenase]] | [[Category: Gamma-butyrobetaine dioxygenase]] | ||
| - | [[Category: Chowdhury, R | + | [[Category: Chowdhury, R]] |
| - | [[Category: Kochan, G T | + | [[Category: Kochan, G T]] |
| - | [[Category: McDonough, M A | + | [[Category: McDonough, M A]] |
| - | [[Category: Rydzik, A M | + | [[Category: Rydzik, A M]] |
| - | [[Category: Schofield, C J | + | [[Category: Schofield, C J]] |
[[Category: 2-oxoglutarate]] | [[Category: 2-oxoglutarate]] | ||
[[Category: Dioxygenase 1]] | [[Category: Dioxygenase 1]] | ||
Revision as of 14:49, 25 December 2014
Human gamma-butyrobetaine dioxygenase (BBOX1) in complex with Ni(II) and N-(3-hydroxypicolinoyl)-S-(pyridin-2-ylmethyl)-L-cysteine (AR692B)
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