2koe
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2koe]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KOE FirstGlance]. <br> | <table><tr><td colspan='2'>[[2koe]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KOE FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2koe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2koe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2koe RCSB], [http://www.ebi.ac.uk/pdbsum/2koe PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2koe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2koe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2koe RCSB], [http://www.ebi.ac.uk/pdbsum/2koe PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CNR1_HUMAN CNR1_HUMAN]] Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.<ref>PMID:15620723</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Deshmukh, L | + | [[Category: Deshmukh, L]] |
| - | [[Category: Janero, D | + | [[Category: Janero, D]] |
| - | [[Category: Makriyannis, A | + | [[Category: Makriyannis, A]] |
| - | [[Category: Tiburu, E | + | [[Category: Tiburu, E]] |
| - | [[Category: Tyukhtenko, S | + | [[Category: Tyukhtenko, S]] |
| - | [[Category: Vinogradova, O | + | [[Category: Vinogradova, O]] |
[[Category: Gpcr]] | [[Category: Gpcr]] | ||
[[Category: Hcb1]] | [[Category: Hcb1]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 14:51, 25 December 2014
Human cannabinoid receptor 1 - helix 7/8 peptide
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