1oxj

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1oxj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OXJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1oxj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OXJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oxj RCSB], [http://www.ebi.ac.uk/pdbsum/1oxj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oxj RCSB], [http://www.ebi.ac.uk/pdbsum/1oxj PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SMG_DROME SMG_DROME]] Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevent their translation. Prevents translation of unlocalized nos in the bulk cytoplasm via the recruitment of cup.<ref>PMID:10488336</ref> <ref>PMID:10606265</ref> <ref>PMID:8895661</ref> <ref>PMID:14685270</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Aggarwal, A K.]]
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[[Category: Aggarwal, A K]]
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[[Category: Gardner, C D.]]
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[[Category: Gardner, C D]]
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[[Category: Green, J B.]]
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[[Category: Green, J B]]
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[[Category: Wharton, R P.]]
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[[Category: Wharton, R P]]
[[Category: Phat domain]]
[[Category: Phat domain]]
[[Category: Rna binding protein]]
[[Category: Rna binding protein]]
[[Category: Rna-binding protein]]
[[Category: Rna-binding protein]]
[[Category: Sam domain]]
[[Category: Sam domain]]

Revision as of 15:02, 25 December 2014

Crystal structure of the Smaug RNA binding domain

1oxj, resolution 1.80Å

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